Laboratory founded in 2015 year at the phase of the Federal Research Center for Fundamental and Translational Medicine (FIC FTM) in g. Novosibirsk.

AT 2021 In 1999, by decision of the Competition Commission of the Ministry of Education and Science, the laboratory acquired the status of "Youth" with the allocation of a grant from the Federal budget within the framework of the national project "Science and Universities". The laboratory is part of the world-class Scientific and Educational Center "Siberian Biotechnological Scientific and Educational Center" (presentation at a meeting of the Council of Young Scientists under the Government of the Novosibirsk Region 14.10.2021)

Main areas of work:

emerging viruses (emerging/re-emerging viruses), including the bird flu virus, paramyxoviruses and animal coronaviruses. Two large international projects are underway in the laboratory (Japan, China) in a new emerging field of science "Global virome" (Global virome); a number of Russian projects (RFFI, RNF).

A series of works in the international team on metagenomic studies of the microbiome of wild and domestic birds of various species, which are the main reservoir of a number of zoonotic infections, the main results are published in a series of articles.

The laboratory is the leading Russian team in the field of molecular epidemiology and ecology of animal influenza viruses. A monograph on the ecology of the influenza virus in Siberia was published- 2016 (From Marco, M.A., Sharshov, K., Gulyaeva, M., Delog, M., Ciccarese, L., Castrucci, M.R., Shestopalov, A. Ecology of avian influenza viruses in Siberia (2016) Siberia: Ecology, Diversity and Environmental Impact, pp. 83-160. )

Research methods – molecular biological, virological, serological, cultural, immunohistochemical.

Sharshov Kirill Alexandrovich graduated in 2005 Tomsk State University and after graduation he was hired by the SSC VB "Vector", where he went from trainee researcher to head of the laboratory. In August 2013 resigned from the SSC VB "Vector" and was hired as a senior researcher in the department of experimental modeling and pathogenesis of infectious diseases of the Federal State Budgetary Institution "SC CEM" of the Siberian Branch of the Russian Academy of Medical Sciences, where through 2 headed the laboratory.

AT 2005-2008 years. Studied at the full-time postgraduate course of the SSC VB "Vector" with a degree in virology. AT 2010-2011 years. Kirill Alexandrovich completed professional retraining courses under the program "Primary specialization of doctors and biologists in working with pathogens of especially dangerous viral infections" (Federal Budgetary Institution SSC VB "Vector" of Rospotrebnadzor).

In March 2010 G. defended his Ph.D. thesis "Biological diversity of strains of the H5N1 influenza virus subtype, allocated in Russia in 2005-2009 years. from wild and domestic birds.

The main focus of the work of Sharshov K.A.. includes, but not limited, the following topics:

– monitoring of a range of zoonotic infections;

– molecular epidemiology of viruses;

– pathogenesis of infectious diseases (animal models)

-diagnosis of some significant viral diseases using molecular biological and immunological methods.

Kirill Alexandrovich takes an active part in the development of scientific agreements, writing and implementation of scientific projects for federal target program competitions, RNF, RFFI. Participates in planning, development and implementation of expeditionary work to collect material. Has experience in international projects (see list below) and more 15 business trips abroad (conferences, internships, field and experimental work). Takes part in teaching activities. Has a number of awards and nominal grants, more 150 scientific works, more 10 invention patents. Supervisor 3 graduate students.

He is an expert of the Russian Science Foundation (RNF).

Awards and achievements of the head of the laboratory:

1. Nomination from the Russian Federation in the international competition ASPIRE 2021. https://www.apec.org/aspire/aspire2021/2021ASPIREnominees
2. Nomination from the Russian Federation for the 7th BRICS YSF Award in Biomedicine at the BRICS International Forum – 7th BRICS Young Scientist Forum with the report "Avian influenza, COVID-19 and other biological threats in Asia: International cooperation»
3. He is the official coordinator of the Russian sector of the World Society of Virology (Membership Review Committee; Coordinator of Russian Sector of the World Society of Virology) – https://www.ws-virology.org/about-us/membership-review-committee/
4. Member of the organizing committee of the Russian branch of the International Center for Research and Early Warning of Influenza, Beijing, Chinese Academy of Sciences (CAS Center for Influenza Research and Early-warning – CASCIRE) With 2017 of the year. https://link.springer.com/article/10.1007%2Fs11427-017-9251-2
5. Member of the European Society for Clinical Microbiology and Infectious Diseases (European Society of Clinical Microbiology and Infectious Diseases);
6. Winner of the competition. N.K. Koltsova. Diploma of II degree for the best scientific work (Directorate FGUN GNC VB “Vector”, 2010 Mr.).
7. Nominal award of the science city Koltsovo named after. Academician L.S.. Sandakhchiev for significant scientific results of a fundamental and applied nature (Administration of the Science City Koltsovo, 2010 Mr.).
8. Prize winner. N.K. Koltsova. Diploma of III degree for success in scientific work (Directorate FGUN GNC VB “Vector”, 2011 Mr.).
9. Nominal grant from the Government of the Novosibirsk Region Governor of the Novosibirsk Region 2013 G. for the implementation of an innovative project (2013).

Projects of the head of the laboratory:

Head of the International Russian-Japanese Project: RNF № 17-44-07001 "Forecasting the spread of avian influenza in Russia and Japan for prevention and control: the role of the East Asian-Australian flyway in gene translocation and influenza virus reassortment”, 2017-2019 (head Sharshov K.A.)

Head of the International Russian-Japanese Project: RNF № 20-44-07001 "Spread of avian RNA viruses in North Asia and the Asia-Pacific region: genetic diversity, pathogenic potential and predicting the impact on poultry farming”, 2020-2022 (head Sharshov K.A.)

Supervisor 4 Russian projects:

RNF 19-74-10055 “Comparative genomics, phylogeographic patterns and pathogenic potential of modern variants of Pneumoviridae viruses” (head Sharshov K.A.)

RFFI 16-34-00306\16 "Reassortant influenza viruses of Central Asia: structural and functional features and evolutionary dynamics of conservative segments”, 2016-2017 (head Sharshov K.A.)

RFBR 17-04-01919_A “Features of the formation of a heterologous gene pool of RNA-containing ortho- and paramyxoviruses in aquatic mammals of the Caspian Sea”, 2017-2019 (head Sharshov K.A.)

including, regional project : Nominal grant from the Government of the Novosibirsk Region “Studying the epidemic significance of influenza viruses, circulating in the Novosibirsk region in the epidemic season 2013-2014 years”, 2013-2014 (head Sharshov K.A.)

Publications

Laboratory staff

1. Kurskaya Olga Grigorievna
   Senior Researcher, Candidate of Medical Sciences
2. Solomatina Maria Vladimirovna
   Senior Researcher, candidate of biological sciences
3. Murashkina Tatyana Alexandrovna
   junior researcher, graduate student
4. Dubovitsky Nikita Artemevich
   junior researcher, graduate student
5. Derko Anastasia Alexandrovna
   junior researcher, graduate student
6. Zhirov Dmitry Alexandrovich
   junior researcher, graduate student
7. Kolotygin Ilya Olegovich
   junior researcher, graduate student
8. Loginova Arina Maksimovna
   Research laboratory assistant
9. Liskevich Anastasia Alexandrovna
   Research laboratory assistant
10. Maneeva Ekaterina Pavlovna
    Research laboratory assistant
11. Meshcheryakova Daria Mikhailovna
    Research laboratory assistant