The institute was established in October 1998 G. based on the unification of the Research Institute of Molecular Pathology and Ecological Biochemistry (year of formation 1992) and Research Institute of Medical and Biological Cybernetics (year of formation 1992) Siberian Branch of the Russian Academy of Medical Sciences.

AT 2018 year, the Institute became part of the FIC FTM as a structural subdivision. Work at the Institute 66 employees, including 39 scientific staff, of them 2 Academician of the Russian Academy of Sciences,1 corresponding member. RAS, 9 doctors and 14 PhDs.